Αναστάσης Στεφάνου
Καθηγητής, Μοριακή και Κυτταρική Βιολογία
22559412
The School of Medicine
Department of Medicine
Ακαδημαϊκα Προσοντα
| Ακαδημαϊκός Τίτλος | Έτος | Ίδρυμα | Τμήμα | Τίτλος Διατριβής (Καταχωρείται προαιρετικά) |
| PhD (Molecular Biology) | 1989-1992 | Charing Cross & Westminster Med Sch (Λονδίνο) | Medicine | Neuro-Immuno Communication |
| MSc (Molecular Biology) | 1988 -1990 | Birkbeck College (London) | Biology | Neuropeptide Expression in Lymphocytes |
| BSc 2:1 (Immunology/Biochemistry) | 1981 -1985 | North East London Polytech |
Ιστορικο Εργοδοτησης
| Περίοδος Εργοδότησης | Εργοδότης | Τόπος | Θέση | |
| Από | Μέχρι | |||
| 2013 | present | School of Medicine, European University Cyprus | Nicosia | Professor (Cell Biology & Genetic) |
| 2005 | 2013 | Medical Molecular Biology Unit, Institute of Child Health, UCL | London | Reader/Associate professor (Molecular & Cellular Biology) |
| 2002 | 2005 | Institute of Child Health, University College London (UCL) | London | Lecturer in the Medical Molecular Biology Unit |
Δημοσιευσεις
| Έτος | Τίτλος | Άλλοι συγγραφείς | Επιστημονικό Περιοδικό και Εκδότης / Συνέδριο |
| 2018 | Annonacin promotes selective cancer cell death via NKA-dependent and SERCA-dependent pathways | .Yiallouris A, Patrikios I, Johnson EO, Sereti E, Dimas K, De Ford C, Fedosova NU, Graier WF, Sokratous K, Kyriakou K, Stephanou A. | . (2018) Cell Death Dis. 9(7):764. doi: 10.1038 |
| 2017 | Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK. | Bourke LT, McDonnell T, McCormick J, Pericleous C, Ripoll VM, Giles I, Rahman A, Stephanou A, Ioannou Y. | Cell Death Dis.;8(1):e2549. doi: 10.1038. |
| 2015 | Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation. | Bourke L, McCormick J, Taylor V, Pericleous C, Blanchet B, Costedoat-Chalumeau N, Stuckey D, Lythgoe MF, Stephanou A, Ioannou Y. | PLoS One 10(12):e0143771. doi: 10.1371. |
| 2015 | MultiElec: A MATLAB Based Application for MEA Data Analysis. | Georgiadis V, Stephanou A, Townsend PA, Jackson TR | PLoS One.;10(6):e0129389. doi: 10.1371. |
| 2014 | Cardiac tissue engineering: renewing the arsenal for the battle against heart disease. | Georgiadis V, Knight RA, Jayasinghe SN, Stephanou A. | Integr Biol (Camb). 2):111-26. doi: 10.1039 |
| 2004 | Epigallocatechin-3-gallate Inhibits STAT1 Activation and Protects the myocardium from Ischemia/Reperfusion–Induced Apoptosis. | Townsend, P. Davidson, S. Scarabelli, Knight, R.A., Latchman, D.S., Stephanou, A. | FASEB J. 18:1621-1623. |
| 2004 | STAT1 interacts with p53 to enhance DNA damage –induced apoptosis. | Townsend, P. Davidson, S. Scarabelli, Knight, R.A., Latchman, D.S., Stephanou, A. | J. Biol Chem. 297:5811-5819. |
| 2002 | Different signalling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischaemia/reperfusion injury. | Scarabelli TM, Stephanou A, Pasini E, Comini L, Raddino R, Knight RA, Latchman DS. | Circ Res. 90:745-748. |
| 2001 | Distinct initiator caspases are required for the induction of apoptosis in cardiac myocytes during ischaemia versus reperfusion injury. | Stephanou, A., Brar, B. Scarabelli, T., Knight, R.A. & Latchman, D.S. | Cell Death & Differentiation 8, 434-435. |
| 2000 | Ischaemia-induced STAT1 expression and activation plays a critical role in cardiac myocyte apoptosis. | Stephanou, A., Brar, B., Knight, R.A., Marber, M.S. Yellon, D. & Latchman, D.S. (2000). | J. Biol Chem 275. 10002-10008. |
Εκθεσεις
Ερευνητικα Projects
| Ημερομηνία | Τίτλος | Επιχορήγηση Από: | Ρόλος στο Ερευνητικό Projects * |
| Jan 2012-Jan 2015 | Bio-electrospraying Cardiac Cells: a novel direct tissue engineering and regenerative medicinal approach for bio-repairing the heart.. £265,101. | British Heart Foundation New Horizons grant. | A.S Principle Investigator |
| Feb 2009- Jan 2012 | Role of p53 and STAT1 in regulating the autophagic pathway in the ischaemic myocardium. | British Heart Foundation Project Post-doc grant. PG/08/091/26002. | Principle Investigator |
| May 2008-April 2011 | Bio-electrospraying: a novel approach in cardiac tissue engineering £126, 082 | British Heart Foundation Project Post-doc grant. PG/07/111/24002. | A.S Principle Investigator |
| July 2006-June 2008 | The role of autophagy in the ischaemic myocardium. £106,904. | British Heart Foundation Project post-doc grant PG/05/118/19834. | Principal supervisor |
| March 2005- February 2008 | Role of STAT1 interaction with p53 family members during ischaemia/reperfusion injury in the myocardium. £139,166. | British Heart Foundation Project Post-doc grant PG/04/077/17362 | Principal Investigator |