Αντωνία Σοφοκλέους
Επίκουρη Καθηγήτρια, Βιοχημεία
22559614
The School of Sciences
Department of Life Sciences
Ακαδημαϊκα Προσοντα
| Ακαδημαϊκός Τίτλος | Έτος | Ίδρυμα | Τμήμα | Τίτλος Διατριβής (Καταχωρείται προαιρετικά) |
| Doctor of Philosophy (PhD) in Molecular Medicine | 2005-2009 | The University of Edinburgh | Department of Rheumatic Diseases, UK | The Role of Cannabinoid Receptor 2 (CB2) in Bone Metabolism |
| Bachelor of Science (BSc Hons) in Molecular Biology and Biochemistry | 2001-2004 | Durham University | Department of Biological Sciences, UK |
Ιστορικο Εργοδοτησης
| Περίοδος Εργοδότησης | Εργοδότης | Τόπος | Θέση | |
| Από | Μέχρι | |||
| 2016 | Σήμερα | Ευρωπαϊκό Πανεπιστήμιο Κύπρου | Σχολή Θετικών Επιστημών | Λέκτορας Βιοχημείας |
| 2016 | Σήμερα | The University of Edinburgh, CGEM, IGMM | Department of Rheumatic Disease | Honorary Fellow |
| 2009 | 2016 | The University of Edinburgh, CGEM, IGMM | Department of Rheumatic Diseases | Post Doctoral Research Fellow |
Δημοσιευσεις
| Έτος | Τίτλος | Άλλοι συγγραφείς | Επιστημονικό Περιοδικό και Εκδότης / Συνέδριο | Τόμος | Σελ. |
| 2019 | Raman spectroscopy as a predictive tool for monitoring osteoporosis therapy in a rat model of postmenopausal osteoporosis | Beattie J.R., Sophocleous A., Caraher M.C., O'Driscoll O., Cummins N.M., Bell S.E.J., Towler M., Rahimnejad Yazdi A., Ralston S.H., Idris A.I. | J Mater Sci Mater Med. | 30(2): 25 | NA |
| 2018 | Raman spectroscopy predicts the link between claw keratin and bone collagen structure in a rodent model of oestrogen deficiency. | Caraher M.C., Sophocleous A., Beattie J.R., O'Driscoll O., Cummins N.M., Brennan O., O'Brien F.J., Ralston S.H., Bell S.E.J., Towler M., Idris A.I. | Biochim. Biophys. Acta | 1864 (2) | 398-406 |
| 2017 | Combined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition. | Sophocleous A., Marino S., Kabir D., Ralston S.H. and Idris A.I. | Ageing Cel | 16 (5) | 1051-1061. |
| 2017 | Heavy cannabis use is associated with low bone mineral density and an increased risk of fractures. | Sophocleous A., Robertson R., Ferreira N.B., McKenzie J., Fraser W.D. and Ralston S.H. | Am. J. Med. | 130 (2) | 214-221 |
| 2015 | Bone cell-autonomous contribution of type 2 cannabinoid receptor to breast cancer induced osteolysis. | Sophocleous A., Marino S., Logan J.G., Mollat P., Ralston S.H. and Idris A.I. | Journal of Biological Chemistry | 290 (36) | 22049-22060 |
| 2015 | The type 2 cannabinoid receptor regulates susceptibility to osteoarthritis in mice. | Sophocleous A., Börjesson A.E., Salter D.M. and Ralston S.H. | Osteoarthritis and Cartilage | 23 (9) | 1586-1594. |
| 2014 | Rodent models of osteoporosis. | Sophocleous A. and Idris A.I. | BoneKEy Reports | 3 | 614 |
| 2014 | Modulation of strain-specific differences in gene expression by cannabinoid type 2 receptor deficiency. | Sophocleous A., Sims A.H., Idris A.I. and Ralston S.H. | Calcified Tissue International | 94 (4) | 423-432. |
| 2011 | The type 2 cannabinoid receptor regulates bone mass and ovariectomy-induced bone loss by affecting osteoblast differentiation and bone formation. | Sophocleous A., Landao-Bassonga E., van’t Hof R.J., Idris A.I. and Ralston S.H. | Endocrinology | 152 (6) | 2141-2149 |
| 2009 | Cannabinoid receptor type 1 protects against age-related bone loss by regulating osteoblast and adipocyte differentiation in marrow stromal cells. | Idris A.I., Sophocleous A., Landao-Bassonga E., Canals M., Milligan G.I., Baker D., van’t Hof R.J. and Ralston S.H. | Cell metabolism | 10 | 139-147 |
Εκθεσεις
Ερευνητικα Projects
| Ημερομηνία | Τίτλος | Επιχορήγηση Από: | Ρόλος στο Ερευνητικό Projects * |
| Ιούλιο 2016 – Σήμερα | The role of microbiome in osteoarthritis development | Genomic and Experimental Medicine (CGEM), University of Edinburgh | Επιστημονικός συντονιστής |
| 02/01/2008 - 01/07/2015 | Regulation of bone metabolism by cannabinoid receptors: mechanisms of action and implications for the treatment of bone disease | Arthritis Research UK | Ερευνητής |
Ακαδημαϊκες Συμβουλευτικες Υπηρεσιες/Συμμετοχη σε Συμβουλια/Επιτροπές
| Περίοδος | Οργανισμός | Τίτλος Θέσης ή Υπηρεσίας | Κύριες Δραστηριότητες |
| Ιανουάριος 2019 – Σήμερα | HubLE (The IFMRS knowledge platform); IFMRS = International Federation of Musculoskeletal Research Societies | Co-chair | Mέλος του συντακτικού συμβουλίου |
| 2011- Σήμερα | Calcified Tissue International (Springer), Frontiers in Endocrinology (Open Access), Frontiers in Pharmacology (Open Access), PLOS ONE (Open Access), British Journal of Pharmacology (Wiley Online Library), Molecular and Cellular Biochemistry (Springer), BMC Musculoskeletal Disorders (Open Access) | Ομότιμος κριτής (peer reviewer) | Ομότιμος κριτής δημοσιεύσεων |
Βραβευσεις/Διεθνεις Διακρισεις
| Date | Title | Awarded by: |
| 2013 | 40th European Symposium on Calcified Tissues | Λισαβόνα, Πορτογαλία |
| 2012 | 39th European Symposium on Calcified Tissues | Στοκχόλμη, Σουηδία |
| 2011 | 3rd joint meeting ECTS/IBMS | Αθήνα, Ελλάδα |
| 2010 | 10th International Meeting on Cancer Induced Bone Disease | Sheffield, Ηνωμένο Βασίλειο |
| 2010 | 37th European Symposium on Calcified Tissues | Glasgow, Ηνωμένο Βασίλειο |
| 2009 | 36th European Symposium on Calcified Tissues | Βιέννη, Αυστρία |
| 2008 | 35th European Symposium on Calcified Tissues | Βαρκελώνη, Ισπανία |
| 2008 | International Bone and Mineral Society | Davos, Ελβετία |
| 2007 | 34th European Symposium on Calcified Tissues | Κοπενγχάγη, Δανία |
Αλλες Διακρισεις
| Ημερομηνία | Τίτλος | Κύριες Δραστηριότητες |
| 2005-2009 | Principal’s Scholarship, University of Edinburgh (Υποτροφία διδακτορικού) | Διδακτορικό (PhD) |