Χριστιάνα Νεοφύτου
Επίκουρη Καθηγήτρια, Βιολογία Καρκίνου
N/A
22713218
Ακαδημαϊκα Προσοντα
| Ακαδημαϊκός Τίτλος | Έτος | Ίδρυμα | Τμήμα | Τίτλος Διατριβής (Καταχωρείται προαιρετικά) |
| DPhil (PhD) in Molecular Biology | 2014 | University of Cyprus | Biological Sciences | Chemotherapeutic mechanism of action of d-alpha Tocopheryl Polyethylene Glycol Succinate (TPGS) in Breast Cancer |
| MSc in Experimental Molecular Biology | 2010 | University of Cyprus | Biological Sciences | Investigation of the apoptotic mechanism induced by natural isoforms and synthetic derivatives of Vitamin E in prostate cancer cell lines |
| BSc in Biology | 2008 | National and Kapodistrian University of Athens | Biology | Investigation of the mechanism of action of Benzopyrene in prostate cancer cell lines |
Ιστορικο Εργοδοτησης
| Περίοδος Εργοδότησης | Εργοδότης | Τόπος | Θέση | |
| Από | Μέχρι | |||
| January 2019 | August 2022 | European University Research Center | Nicosia, Cyprus | Post Doctoral Researcher |
| January 2015 | August 2019 | University of Cyprus | Nicosia, Cyprus | Post Doctoral Researcher |
| 2013 | 2014 | University of Cyprus | Nicosia, Cyprus | Special Scientist |
Δημοσιευσεις
| Έτος | Τίτλος | Άλλοι συγγραφείς | Επιστημονικό Περιοδικό και Εκδότης / Συνέδριο | Τόμος | Σελ. |
| 2022 | Amygdalin acts as a chemoprotective agent in combination with the platinum drug Cisplatin | Christodoulou P, Boutsikos P, Neophytou CM, Kyriakou TC, Christodoulou M, Papageorgis P, Stephanou A, Patrikios I | Frontiers in Pharmacology | 3996 | |
| 2022 | The Use of Human Biomonitoring to Assess Occupational Exposure to PAHs in Europe: A Comprehensive Review | Louro, H., B. C. Gomes, A. T. Saber, A. L. Iamiceli, T. Goen, K. Jones, A. Katsonouri, Neophytou C. M., U. Vogel, C. Ventura, A. Oberemm, R. C. Duca, M. F. Fernandez, N. Olea, T. Santonen, S. Viegas and M. J. Silva | Toxics | 10 | 8 |
| 2022 | LC-HRMS/MS phytochemical profiling of Vernonia kotschyana Sch. Bip. ex Walp.: Potential involvement of highly-oxygenated stigmastane-type saponins in cancer cell viability, apoptosis and intracellular ROS production. | Vasincu A, Luca SV, Charalambous C, Skalicka-Woźniak K, Miron A. | South African Journal of Botany | 144 | 83-91 |
| 2021 | Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance | Trougakos I., Nuray E., and Papageorgis P. | Cancers | 13 | 17 |
| 2021 | Anti-Cancer Activity and Phenolic Content of Extracts Derived from Cypriot Carob (Ceratonia siliqua L.) Pods Using Different Solvents | Gregoriou G., Vasincu A., Gregoriou Y., Hatzipakkou H., Pinakoulaki E., Stavrou I., Christou A., Kapnisi C., Aigner S., Stuppner H., Kakas A., Constantinou A.I. | Molecules | 26 | (16), 5017 |
| 2019 | d-a-Tocopheryl Polyethylene Glycol 1000 Succinate and a small-molecule Survivin suppressant synergistically induce apoptosis in SKBR3 breast cancer cells | Mesaritis A., Gregoriou G., Constantinou A.I | Scientific Reports | 9(1) | 14375 |
| 2019 | Mechanisms of Metastatic Tumor Dormancy and Implications for Cancer Therapy | Kyriakou TC, Papageorgis P | International journal of molecular sciences | 20 | 24 |
| 2018 | Molecular mechanisms and emerging therapeutic targets of triple-negative breast cancer metastasis | Mpoutsikos P., and Papageorgis P | Frontiers in Oncology | 8 | 31 |
| 2015 | Targeting IL13Ra2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis | Papageorgis P., Ozturk S., Lambert A.W., Tzatsos A., Wong C.K., Thiagalingam S. and Constantinou A.I., | Breast Cancer Research | 17(1) | 98 |
| 2014 | D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells | Constantinou C., Papageorgis P., Constantinou A.I., | Biochemical Pharmacology, 2014. | 89 | 31-42 |
Εκθεσεις
| Ημερομηνία | Θέμα | Διεθνής / Τοπική | Τοποθεσία* | Ρόλος στην Έκθεση |
| 18-20 November 2021 | Unveiling the transcriptional landscape that regulates colonization of dormant metastatic breast cancer cells to the lungs | International | 9th International Multithematic Scientific Bio-Medical Congress (IMBMC), Nicosia, Cyprus. | Invited talk |
| 5-9 September 2021 | Unveiling the role of ATF4 in metastatic breast cancer dormancy | International | 4th Annual Conference of STRATAGEM “New Diagnostic and Therapeutic Tools against Multi-Drug Resistant Tumours”, Prague | Invited talk |
| 4-5th of December, 2020 | Unveiling novel molecular mechanisms that regulate colonization of dormant metastatic breast cancer cells | International | 8th International Conference of The Cyprus Society of Human Genetics, online | Invited talk |
| 7-9 November 2019 | Experimental Strategies to Unveil Novel Molecular Mechanisms that Regulate Colonization of Dormant Metastatic Breast Cancer Cells | Local | 7th International Multithematic Bio-Medical Congress (IMBMC), Nicosia, Cyprus. | Poster Presentation |
| 24-26 June 2019 | Unveiling novel molecular mechanisms that regulate colonization of dormant metastatic breast cancer cells | Local | Advances in the Applications of Monoclonal Antibodies in Clinical Oncology, Grecian Park Hotel, Konnos Bay, Cyprus | Invited talk |
| 1 - 3 February 2018 | d-α-tocopheryl polyethylene glycol 1000 succinate and a small molecule inhibitor of survivin synergistically induce apoptosis in breast cancer cells | International | EARC conference series, A Matter of Life or Death: From Basic Cell Death Mechanisms to Novel Cancer Treatments, Amsterdam, Netherlands | Poster Presentation |
| 28 November 2017 | Development of a novel therapeutic approach for breast cancer based on the nano-formulation of a Small Molecule Inhibitor (SMI) of an anti-apoptotic protein | Local | 3rd INNOVATION & ENTREPRENEURSHIP FORUM, University of Cyprus | Poster Presentation |
| November 3rd, 2017 | Nanoparticle applications in cancer chemoprevention and therapy | Local | 5th International Bio-Medical Scientific Cyprus Congress, Nicosia | Invited talk |
| March 13-16, 2013 | Application of computational modeling for identifying promising agents to control breast cancer | International | 13th St. Gallen International Breast Cancer Conference, St Gallen, Switzerland. | Poster Presentation |
| March 2012 | D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces apoptosis and cell cycle arrest selectively in breast cancer cells by targeting aberrantly activated pathways engaging survivin signaling. | International | Proceedings of the American Assoc. Cancer Res. 53:1190, 2012. | Poster Presentation |
Ερευνητικα Projects
| Ημερομηνία | Τίτλος | Επιχορήγηση Από: | Ρόλος στο Ερευνητικό Projects * |
| 2022-2024 | Targeting the desmoplastic tumor microenvironment to improve the efficacy of pancreatic cancer immunotherapy. | The Research & Innovation Foundation | Researcher |
| 2021-2022 | Examination of the chemopreventive and anti-cancer properties of plant extracts. | Alpinamed | Researcher |
| 2019-2021 | Unveiling novel molecular mechanisms that regulate colonization of dormant metastatic breast cancer cells | The Research & Innovation Foundation | Researcher |
| 2017-2021 | The European Human Biomonitoring Initiative | The European Commission | Researcher |
| 2015-2019 | Epigenetic Chemical Biology COST | The European Commission | Researcher |
| 2011-2014 | A Social Collaborative Working Space Semantically Interlinking Biomedical Researchers, Knowledge and Data for The Design and Execution of In-Silico Models and Experiments in Cancer Chemoprevention | The European Commission | Researcher |
Ακαδημαϊκες Συμβουλευτικες Υπηρεσιες/Συμμετοχη σε Συμβουλια/Επιτροπές
| Περίοδος | Οργανισμός | Τίτλος Θέσης ή Υπηρεσίας | Κύριες Δραστηριότητες |
| 2021-2024 | Lobular Breast Cancer: Discovery Science, Translational Goals, Clinical Impact | The European Commission | Management Committee member |
| 2019-2022 | New diagnostic and therapeutic tools against multidrug resistant tumors | The European Commission | Management Committee member |
Βραβευσεις/Διεθνεις Διακρισεις
| Date | Title | Awarded by: |
| 2021 | Third Prize for the Best Oral Presentation for the talk “Unveiling the Role of ATF4 in Metastatic Breast Cancer Dormancy” | 4th Annual Conference of STRATAGEM “New Diagnostic and Therapeutic Tools against Multi-Drug Resistant Tumours” |
| 2019 | Second place prize for the poster presentation “Experimental Strategies to Unveil Novel Molecular Mechanisms that Regulate Colonization of Dormant Metastatic Breast Cancer Cells” | European University Cyprus at the 7th International Multithematic Bio-Medical Congress (IMBMC), |
| 2017 | Second place award for the abstract entitled synergistic effect of d-α-tocopheryl polyethylene glycol 1000 succinate and a small molecule inhibitor of survivin in breast cancer | The 3rd Cyprus Oncology Conference |
| 2016 | 1st Place award in the category of Post-Doctoral fellows | The Molecular Medicine Research Center University of Cyprus as part of the Euro-BioCy Research Proposal Competition. |
| 2015 | New Researcher Grant for the submission of a research proposal to the Horizon2020 Call “H2020-PHC-2015-two-stage” under the topic PHC-14-2015. | University of Cyprus |
| 2013 | New Researcher Grant for the submission of a research proposal to the MARIE CURIE ACTIONS-PEOPLE Call: FP7-PEOPLE-2013-IAPP Industry-Academia Partnerships and Pathways (IAPP). | University of Cyprus |
| 2010 | 1st Poster award for the poster presentation at the 10th Marianna Lordos Symposium | Marianna Lordos Cancer Memorial Fund. |
| 2010 | Award for the highest GPA obtained in the MSc in Experimental Biology Graduating class of 2010 | C.Georgiou (Lab Supplies) LTD. |